Anti-RMND5A Polyclonal Antibody - SAlexa Fluor 647
Cat: K114842P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-RMND5A Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：64795 | 【Swiss Prot】：Q9H871 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RMND5A | |
| 【Public Immunogen Range】：1-99aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
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