Anti-CTU1 Polyclonal Antibody - RBITC
Cat: K115004P - RBITC
Summary:
| 【Product name】：Anti-CTU1 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：90353 | 【Swiss Prot】：Q7Z7A3 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CTU1 | |
| 【Public Immunogen Range】：298-348/348aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys)，tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs，an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
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