Anti-OAS1 Polyclonal Antibody
Cat: K115116P
Summary:
| 【Product name】：Anti-OAS1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4938 | 【Swiss Prot】：P00973 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human OAS1 | |
| 【Public Immunogen Range】：200-250/400aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This interferon-induced gene encodes a protein that synthesizes 2’，5’-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response，and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection，including SARS-CoV-2，and diabetes mellitus，type 1. This gene is located in a cluster of related genes on chromosome 12.
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