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Anti-RSPO1 Polyclonal Antibody - SAlexa Fluor 568
Cat: K115118P - SAlexa Fluor 568
Summary:
【Product name】:Anti-RSPO1 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:284654 【Swiss Prot】:Q2MKA7
【Observed】:20/29kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000.IHC 1:50-200.
【Immunogen】:A synthetic peptide of human RSPO1
【Public Immunogen Range】:20-70/263aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a secreted activator protein with two cysteine-rich,furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice,the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing,providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
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