Anti-RSPO1 Polyclonal Antibody - SAlexa Fluor 647
Cat: K115118P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-RSPO1 Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：284654 | 【Swiss Prot】：Q2MKA7 |
| 【Observed】：20/29kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human RSPO1 | |
| 【Public Immunogen Range】：20-70/263aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a secreted activator protein with two cysteine-rich，furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice，the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing，providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
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