Anti-MITF Polyclonal Antibody - SAlexa Fluor 488
Cat: K115141P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-MITF Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：4286 | 【Swiss Prot】：O75030 |
| 【Observed】：59kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human MITF | |
| 【Public Immunogen Range】：200-250/526aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes，such as Waardenburg syndrome type 2 and Tietz syndrome.
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