Anti-BECN1 Polyclonal Antibody
Cat: K115171P
Summary:
| 【Product name】：Anti-BECN1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8678 | 【Swiss Prot】：Q14457 |
| 【Observed】：63kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human BECN1 | |
| 【Public Immunogen Range】：141-450aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a protein that regulates autophagy，a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes，including tumorigenesis，neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
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