Anti-EDEM3 Polyclonal Antibody - Biotin
Cat: K115208P - Biotin
Summary:
| 【Product name】：Anti-EDEM3 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：80267 | 【Swiss Prot】：Q9BZQ6 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human EDEM3 | |
| 【Public Immunogen Range】：1-122aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes，by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans (PubMed:25092655).May also participate in mannose trimming from all glycoproteins and not just misfolded ones targeted to ERAD (PubMed:34143952).May have alpha 1，2-mannosidase activity (By similarity).
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