Anti-D2HGDH Polyclonal Antibody - Cy7
Cat: K115246P - Cy7
Summary:
| 【Product name】：Anti-D2HGDH Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：728294 | 【Swiss Prot】：Q8N465 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human D2HGDH | |
| 【Public Immunogen Range】：302-521aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes D-2hydroxyglutarate dehydrogenase，a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme，which is most active in liver and kidney but also active in heart and brain，converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria，a rare recessive neurometabolic disorder causing developmental delay，epilepsy，hypotonia，and dysmorphic features.
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