Anti-FYCO1 Polyclonal Antibody
Cat: K115265P
Summary:
| 【Product name】：Anti-FYCO1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79443 | 【Swiss Prot】：Q9BQS8 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human FYCO1 | |
| 【Public Immunogen Range】：1-256aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain，a FYVE-type zinc finger domain，and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7，phosphatidylinositol-3-phosphate (PI3P)，the autophagosome marker LC3，and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2).
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