Anti-HLA-G Polyclonal Antibody - Biotin
Cat: K115308P - Biotin
Summary:
| 【Product name】：Anti-HLA-G Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3135 | 【Swiss Prot】：P17693 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human HLA-G | |
| 【Public Immunogen Range】：50-100/338aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide，exons 2 and 3 encode the alpha1 and alpha2 domain，which both bind the peptide，exon 4 encodes the alpha3 domain，exon 5 encodes the transmembrane region，and exon 6 encodes the cytoplasmic tail.
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