Anti-ATP6V1H Polyclonal Antibody - SAlexa Fluor 488
Cat: K115314P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-ATP6V1H Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51606 | 【Swiss Prot】：Q9UI12 |
| 【Observed】：50kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human ATP6V1H | |
| 【Public Immunogen Range】：340-390/483aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase)，a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002).V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types，is targeted to the plasma membrane，where it is responsible for acidifying the extracellular environment (By similarity).Subunit H is essential for V-ATPase activity，but not for the assembly of the complex (By similarity).Involved in the endocytosis mediated by clathrin-coated pits，required for the formation of endosomes (PubMed:12032142).
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