Anti-ICAM3 Polyclonal Antibody - SAlexa Fluor 532
Cat: K115317P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-ICAM3 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3385 | 【Swiss Prot】：P32942 |
| 【Observed】：130kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human ICAM3 | |
| 【Public Immunogen Range】：400-450/547aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins，contain 2-9 immunoglobulin-like C2-type domains，and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule，but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
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