Anti-EIF4E Polyclonal Antibody
Cat: K115319P
Summary:
| 【Product name】：Anti-EIF4E Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1977 | 【Swiss Prot】：P06730 |
| 【Observed】：25kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human EIF4E | |
| 【Public Immunogen Range】：167-217/217aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex，which recognizes the 7-methylguanosine cap structure at the 5’ end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5’-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene，and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
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