Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates.Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity).Plays an important role in G protein-coupled receptor signaling pathways involving GNAQ and potentially other heterotrimeric G proteins by regulating their dynamic association with the plasma membrane.Palmitoylates ITGA6 and ITGB4，thereby regulating the alpha-6/beta-4 integrin localization，expression and function in cell adhesion to laminin.Plays a role in the TRAIL-activated apoptotic signaling pathway most probably through the palmitoylation and localization to the plasma membrane of TNFRSF10A.In the brain，by palmitoylating the gamma subunit GABRG2 of GABA(A) receptors and regulating their postsynaptic accumulation，plays a role in synaptic GABAergic inhibitory function and GABAergic innervation. Palmito