Background:
Ribosomes,the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein,which is the functional equivalent of the E. coli L10 ribosomal protein,belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers,and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist;they encode the same protein. As is typical for genes encoding ribosomal proteins,there are multiple processed pseudogenes of this gene dispersed through the genome.