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Anti-UNC119 Polyclonal Antibody - Biotin
Cat: K115414P - Biotin
Summary:
【Product name】:Anti-UNC119 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9094 【Swiss Prot】:Q13432
【Observed】:30kDa
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human UNC119
【Public Immunogen Range】:1-150aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Involved in synaptic functions in photoreceptor cells,the signal transduction in immune cells as a Src family kinase activator,endosome recycling,the uptake of bacteria and endocytosis,protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
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