Anti-ACTR1B Polyclonal Antibody - Cy3.5
Cat: K115423P - Cy3.5
Summary:
| 【Product name】：Anti-ACTR1B Polyclonal Antibody - Cy3.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10120 | 【Swiss Prot】：P42025 |
| 【Observed】：49kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:100-500.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ACTR1B | |
| 【Public Immunogen Range】：10-270aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a 42.3 kD subunit of dynactin，a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions，including ER-to-Golgi transport，the centripetal movement of lysosomes and endosomes，spindle formation，chromosome movement，nuclear positioning，and axonogenesis. This subunit，like ACTR1A，is an actin-related protein. These two proteins，which are of equal length and share 90% amino acid identity，are present in a constant ratio of approximately 1:15 in the dynactin complex.
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