Anti-ERCC2 Polyclonal Antibody - Biotin
Cat: K115427P - Biotin
Summary:
| 【Product name】：Anti-ERCC2 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2068 | 【Swiss Prot】：P18074 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ERCC2 | |
| 【Public Immunogen Range】：10-300aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders，the cancer-prone syndrome xeroderma pigmentosum complementation group D，trichothiodystrophy，and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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