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Anti-MAP1LC3A/MAP1LC3B/MAP1LC3B2 Polyclonal Antibody
Cat: K115492P
Summary:
【Product name】:Anti-MAP1LC3A/MAP1LC3B/MAP1LC3B2 Polyclonal Antibody
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:84557/81631/643246 【Swiss Prot】:Q9H492/Q9GZQ8/A6NCE7
【Observed】:Cow
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human MAP1LC3A/MAP1LC3B/MAP1LC3B2
【Public Immunogen Range】:20-70/121aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with MAP1LC3A/MAP1LC3B/MAP1LC3B2 antibody diluted at 1:100.