Anti-CXCR1 Polyclonal Antibody
Cat: K115500P
Summary:
| 【Product name】：Anti-CXCR1 Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3577 | 【Swiss Prot】：P25024 |
| 【Observed】：Chimpanzee | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CXCR1 | |
| 【Public Immunogen Range】：1-51/350aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity， and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene， IL8RB， a gene encoding another high affinity IL8 receptor， as well as IL8RBP， a pseudogene of IL8RB， form a gene cluster in a region mapped to chromosome 2q33-q36.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with CXCR1 antibody diluted at 1:100.