Anti-SIRT3 Polyclonal Antibody
Cat: K115505P
Summary:
| 【Product name】：Anti-SIRT3 Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23410 | 【Swiss Prot】：Q9NTG7 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human SIRT3 | |
| 【Public Immunogen Range】：250-300/399aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases， homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria， where it can eliminate reactive oxygen species， inhibit apoptosis， and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression， cancer， cardiovascular disease， neuroprotection， aging， and metabolic control.
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer with SIRT3 antibody diluted at 1:100.