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Anti-HNRNPD Polyclonal Antibody
Cat: K115534P
Summary:
【Product name】:Anti-HNRNPD Polyclonal Antibody
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3184 【Swiss Prot】:Q14103
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000.IHC 1:50-200.
【Immunogen】:A synthetic peptide of human HNRNPD
【Public Immunogen Range】:50-100/355aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
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