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Anti-JAG1 Polyclonal Antibody
Cat: K115548P
Summary:
【Product name】:Anti-JAG1 Polyclonal Antibody
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:182 【Swiss Prot】:P78504
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human JAG1
【Public Immunogen Range】:680-730/1218aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
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