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Anti-SMARCE1 Polyclonal Antibody
Cat: K115553P
Summary:
【Product name】:Anti-SMARCE1 Polyclonal Antibody
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6605 【Swiss Prot】:Q969G3
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000.IHC 1:50-200.
【Immunogen】:Recombinant protein of human SMARCE1
【Public Immunogen Range】:10-360aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
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