Anti-GRB2 Polyclonal Antibody - SAlexa Fluor 488
Cat: K115564P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-GRB2 Polyclonal Antibody - SAlexa Fluor 488 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2885 | 【Swiss Prot】：P62993 |
| 【Observed】：Chicken | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human GRB2 | |
| 【Public Immunogen Range】：1-218aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins， and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans， which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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