Anti-RUNX3 Polyclonal Antibody - RBITC
Cat: K115644P - RBITC
Summary:
| 【Product name】：Anti-RUNX3 Polyclonal Antibody - RBITC | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：864 | 【Swiss Prot】：Q13761 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human RUNX3 | |
| 【Public Immunogen Range】：365-415/415aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5’-PYGPYGGT-3’ found in a number of enhancers and promoters， and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor， and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
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