Anti-PVR Polyclonal Antibody - Biotin
Cat: K115647P - Biotin
Summary:
| 【Product name】：Anti-PVR Polyclonal Antibody - Biotin | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5817 | 【Swiss Prot】：P15151 |
| 【Observed】：Monkey | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human PVR | |
| 【Public Immunogen Range】：50-100/417aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin， while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage， and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
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