Anti-PGA4/PGA3/PGA5 Polyclonal Antibody - SAlexa Fluor 660
Cat: K115670P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-PGA4/PGA3/PGA5 Polyclonal Antibody - SAlexa Fluor 660 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：643847/643834/5222 | 【Swiss Prot】：P0DJD7/P0DJD8/P0DJD9 |
| 【Observed】：Cow;Pig;Dog;Monkey;Rabbit | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human PGA4/PGA3/PGA5 | |
| 【Public Immunogen Range】：150-200/388aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a protein precursor of the digestive enzyme pepsin， a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme， which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11， each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
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