Anti-PLCG2 Polyclonal Antibody - Cy5
Cat: K115690P - Cy5
Summary:
| 【Product name】：Anti-PLCG2 Polyclonal Antibody - Cy5 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5336 | 【Swiss Prot】：P16885 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human PLCG2 | |
| 【Public Immunogen Range】：650-700/1265aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4，5-bisphosphate to 1D-myo-inositol 1，4，5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation， antibody deficiency， and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
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