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Anti-RELA Polyclonal Antibody - SAlexa Fluor 647
Cat: K115717P - SAlexa Fluor 647
Summary:
【Product name】:Anti-RELA Polyclonal Antibody - SAlexa Fluor 647
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5970 【Swiss Prot】:Q04206
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human RELA
【Public Immunogen Range】:1-247aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
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