This gene product is a member of the serine-arginine (SR) family of proteins， which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs， which are required for binding to RNA， and multiple C-terminal SR/RS repeats， which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS， and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4， 9， 14， 18， and 20. Alternative splicing results in multiple transcript variants.