Anti-CFL1 Polyclonal Antibody
Cat: K115728P
Summary:
| 【Product name】：Anti-CFL1 Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1072 | 【Swiss Prot】：P23528 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human CFL1 | |
| 【Public Immunogen Range】：1-112aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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