Anti-RHOH Polyclonal Antibody
Cat: K115743P
Summary:
| 【Product name】：Anti-RHOH Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：399 | 【Swiss Prot】：Q15669 |
| 【Observed】：Bovine | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human RHOH | |
| 【Public Immunogen Range】：1-192aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells， where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin’s lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3， leading to the production of fusion transcripts. Alternative splicing in the 5’ untranslated region results in multiple transcript variants that encode the same protein.
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