下载
Anti-RHOH Polyclonal Antibody - FITC
Cat: K115743P - FITC
Summary:
【Product name】:Anti-RHOH Polyclonal Antibody - FITC
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:399 【Swiss Prot】:Q15669
【Observed】:Bovine
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human RHOH
【Public Immunogen Range】:1-192aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin’s lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5’ untranslated region results in multiple transcript variants that encode the same protein.
Verified picture: