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Anti-CFL2 Polyclonal Antibody - Biotin
Cat: K115748P - Biotin
Summary:
【Product name】:Anti-CFL2 Polyclonal Antibody - Biotin
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1073 【Swiss Prot】:Q9Y281
【Observed】:Bovine;Pig;Chicken
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human CFL2
【Public Immunogen Range】:1-167aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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