Anti-GTF2IRD1 Polyclonal Antibody - Biotin
Cat: K115759P - Biotin
Summary:
| 【Product name】：Anti-GTF2IRD1 Polyclonal Antibody - Biotin | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9569 | 【Swiss Prot】：Q9UHL9 |
| 【Observed】：Bovine;Chicken;Rabbit;Horse;Sheep | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human GTF2IRD1 | |
| 【Public Immunogen Range】：90-390aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome， a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
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