Anti-DNM1L Polyclonal Antibody - SAlexa Fluor 555
Cat: K115794P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-DNM1L Polyclonal Antibody - SAlexa Fluor 555 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10059 | 【Swiss Prot】：O00429 |
| 【Observed】：A.thaliana | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human DNM1L | |
| 【Public Immunogen Range】：360-710aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division， and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders， including Alzheimer’s disease. Mutations in this gene are associated with the autosomal dominant disorder， encephalopathy， lethal， due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
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