Anti-NCF2 Polyclonal Antibody
Cat: K115806P
Summary:
| 【Product name】：Anti-NCF2 Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4688 | 【Swiss Prot】：P19878 |
| 【Observed】：Bovine | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human NCF2 | |
| 【Public Immunogen Range】：178-527aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes neutrophil cytosolic factor 2， the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene， as well as in other NADPH oxidase subunits， can result in chronic granulomatous disease， a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
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