Anti-DDC Polyclonal Antibody - HRP
Cat: K115864P - HRP
Summary:
| 【Product name】：Anti-DDC Polyclonal Antibody - HRP | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1644 | 【Swiss Prot】：P20711 |
| 【Observed】：Cow;Guinea pig | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human DDC | |
| 【Public Immunogen Range】：330-380/480aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The encoded protein catalyzes the decarboxylation of L-3，4-dihydroxyphenylalanine (DOPA) to dopamine， L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
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