Anti-PROS1 Polyclonal Antibody
Cat: K115915P
Summary:
| 【Product name】：Anti-PROS1 Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5627 | 【Swiss Prot】：P07225 |
| 【Observed】：Bovine;Rabbit | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PROS1 | |
| 【Public Immunogen Range】：40-340aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease， activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free， functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
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