Anti-DNAJB4 Polyclonal Antibody - SAlexa Fluor 405
Cat: K115989P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-DNAJB4 Polyclonal Antibody - SAlexa Fluor 405 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：11080 | 【Swiss Prot】：Q9UDY4 |
| 【Observed】：Bovine | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human DNAJB4 | |
| 【Public Immunogen Range】：11-160aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a molecular chaperone， tumor suppressor， and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma， and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
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