Anti-RETREG1 Polyclonal Antibody - SAlexa Fluor 555
Cat: K116006P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-RETREG1 Polyclonal Antibody - SAlexa Fluor 555 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：54463 | 【Swiss Prot】：Q9H6L5 |
| 【Observed】：Bovine | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RETREG1 | |
| 【Public Immunogen Range】：1-142aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Endoplasmic reticulum (ER)-anchored autophagy regulator which mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720， PubMed:31930741， PubMed:34338405).Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720， PubMed:31930741， PubMed:34338405).Active under basal conditions (PubMed:34338405).Required for collagen quality control in a LIR motif-dependent manner (By similarity).Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196， PubMed:26040720).
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