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Anti-MMP7 Polyclonal Antibody - SAlexa Fluor 532
Cat: K011453P - SAlexa Fluor 532
Summary:
【Product name】:Anti-MMP7 Polyclonal Antibody - SAlexa Fluor 532
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4316 【Swiss Prot】:P09237
【Observed】:Rat
【Tested applications】:IF,IHC,ELISA,WB
【Recommended dilution】:WB 1:500-2000.IHC 1:50-200.IF 1:50-200.ELISA 1:2000-10000.
【Immunogen】:A synthetic peptide of human MMP7
【Public Immunogen Range】:151-250/269aa
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis.Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.The enzyme encoded by this gene degrades proteoglycans fibronectin elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain.The enzyme is involved in wound healing and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.[provided by RefSeq Jul 2008]
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