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Anti-NLRP3 Monoclonal Antibody - HRP
Cat: K011503M - HRP
Summary:
【Product name】:Anti-NLRP3 Monoclonal Antibody - HRP
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:114548 【Swiss Prot】:Q96P20
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:Recombinant protein of human NLRP3
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
May function as an inducer of apoptosis.Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling.Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65.Also inhibits transcriptional activity of RELA.Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.Subcellular Location : Cytoplasm.
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