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Anti-HMGB1 Monoclonal Antibody - SAlexa Fluor 555
Cat: K011504M - SAlexa Fluor 555
Summary:
【Product name】:Anti-HMGB1 Monoclonal Antibody - SAlexa Fluor 555
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3146 【Swiss Prot】:P09429
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human HMGB1
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin.Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix.HMG proteins synergize with Oct-2 members of the NFκB family ATF-2 and c-Jun to activate transcription.
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