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Anti-GSDMD Monoclonal Antibody - Cy3.5
Cat: K011506M - Cy3.5
Summary:
【Product name】:Anti-GSDMD Monoclonal Antibody - Cy3.5
【Isotype】:IgG2a 【Purification】:Affinity purification
【Gene ID】:79792 【Swiss Prot】:P57764
【Tested applications】:IP,IF,WB,ELISA
【Recommended dilution】:WB 1:5000-50000.IF 1:50-500.IP 0.5-4.0 ug.
【Immunogen】:Recombinant protein of human GSDMD
【Public Immunogen Range】:135-484aa
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
VGSDMD is a member of the gasdermin family.Members of this family appear to play a role in regulation of epithelial proliferation.GSDMD has been suggested to act as a tumor suppressor.Recently GSDMD is identified as a new component of inflammasomes and it is an executor of pyroptosis and required for interleukin-1β secretion.Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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