Anti-GSDMD Monoclonal Antibody - SAlexa Fluor 640
Cat: K011506M - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-GSDMD Monoclonal Antibody - SAlexa Fluor 640 | |
| 【Isotype】：IgG2a | 【Purification】：Affinity purification |
| 【Gene ID】：79792 | 【Swiss Prot】：P57764 |
| 【Tested applications】：IP,IF,WB,ELISA | |
| 【Recommended dilution】：WB 1:5000-50000.IF 1:50-500.IP 0.5-4.0 ug. | |
| 【Immunogen】：Recombinant protein of human GSDMD | |
| 【Public Immunogen Range】：135-484aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
VGSDMD is a member of the gasdermin family.Members of this family appear to play a role in regulation of epithelial proliferation.GSDMD has been suggested to act as a tumor suppressor.Recently GSDMD is identified as a new component of inflammasomes and it is an executor of pyroptosis and required for interleukin-1β secretion.Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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