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Anti-GSDMD Monoclonal Antibody - SAlexa Fluor 594
Cat: K011506M - SAlexa Fluor 594
Summary:
【Product name】:Anti-GSDMD Monoclonal Antibody - SAlexa Fluor 594
【Isotype】:IgG2a 【Purification】:Affinity purification
【Gene ID】:79792 【Swiss Prot】:P57764
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human GSDMD
【Public Immunogen Range】:135-484aa
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
VGSDMD is a member of the gasdermin family.Members of this family appear to play a role in regulation of epithelial proliferation.GSDMD has been suggested to act as a tumor suppressor.Recently GSDMD is identified as a new component of inflammasomes and it is an executor of pyroptosis and required for interleukin-1β secretion.Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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