Anti-CHD3(C-term) Monoclonal Antibody
Cat: K000030M
Summary:
| 【Product name】：Anti-CHD3(C-term) Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：1107 | 【Swiss Prot】：Q12873 |
| 【Tested applications】：IP,IF,WB,ICC | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 1:20. ICC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human CHD3(C-term) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Verified picture:
Western blot analysis with CHD3(C-term) antibody diluted at 1:1000;Lane: NTERA-2 3T3 C6 K562 HeLa.
Immunofluorescence analysis of HeLa using CHD3(C-term) antibody diluted at 1:100.
Immunoprecipitation analysis of HeLa extracts using CHD3(C-term) antibody(IP:1:20;WB:1:1000).Control IgG: Normal Mouse IgG.